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Thiamin Diphosphate and Vitamin B1

  1. Susana K Schowen,
  2. K Barbara Schowen,
  3. Richard L Schowen

Published Online: 19 APR 2001

DOI: 10.1038/npg.els.0000651



How to Cite

Schowen, S. K., Schowen, K. B. and Schowen, R. L. 2001. Thiamin Diphosphate and Vitamin B1. eLS. .

Author Information

  1. University of Kansas, Lawrence, Kansas, USA

Publication History

  1. Published Online: 19 APR 2001


Thiamin diphosphate is the active form of thiamin (vitamin B1) required as an enzyme cofactor to assist in fission and formation of carbon–carbon bonds in biosynthetic and bioenergetic reactions.


  • Thiamin;
  • vitamin B1;
  • enzyme cofactor;
  • bioenergetic reactions;
  • carbon–carbon bond cleavage