Metalloenzymes and Electrophilic Catalysis
Published Online: 3 MAY 2005
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Eames, J. and Watkinson, M. 2005. Metalloenzymes and Electrophilic Catalysis. eLS. .
- Published Online: 3 MAY 2005
Enzymes perform a number of remarkable synthetic transformations at neutral pH and ambient temperatures. Many enzymes employ metal ions to aid in electrophilic catalysis. Zinc, the commonest Lewis acid in biochemistry, is an essential cofactor in over 300 enzymes.
- general acid catalysis;
- specific acid catalysis;
- lewis acid catalysis;
- non-redox metalloenzymes