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Xenopus Embryo: Neural Induction

  1. Sally A Moody

Published Online: 19 APR 2001

DOI: 10.1038/npg.els.0000731



How to Cite

Moody, S. A. 2001. Xenopus Embryo: Neural Induction. eLS. .

Author Information

  1. George Washington University, Washington DC, USA

Publication History

  1. Published Online: 19 APR 2001

This is not the most recent version of the article. View current version (15 JUN 2015)


Neural induction is the process by which the embryonic ectoderm is instructed to become the nervous system rather than the epidermis (skin). It is accomplished in two steps via signalling interactions with the adjacent mesoderm; first, dorsal ectoderm acquires an anterior neural fate by the blockade of bone morphogenetic protein (BMP) signalling, and second, the neural ectoderm acquires anterior–posterior polarity via graded concentrations of fibroblast growth factors (FGFs), retinoids and Wnts.


  • organizer;
  • molecular signals;
  • noggin;
  • chordin;
  • cerberus