Xenopus Embryo: Neural Induction
Published Online: 19 APR 2001
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Moody, S. A. 2001. Xenopus Embryo: Neural Induction. eLS. .
- Published Online: 19 APR 2001
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Neural induction is the process by which the embryonic ectoderm is instructed to become the nervous system rather than the epidermis (skin). It is accomplished in two steps via signalling interactions with the adjacent mesoderm; first, dorsal ectoderm acquires an anterior neural fate by the blockade of bone morphogenetic protein (BMP) signalling, and second, the neural ectoderm acquires anterior–posterior polarity via graded concentrations of fibroblast growth factors (FGFs), retinoids and Wnts.
- molecular signals;