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Vitamin K-dependent Carboxylase

  1. John W Suttie

Published Online: 25 APR 2001

DOI: 10.1038/npg.els.0000864

eLS

eLS

How to Cite

Suttie, J. W. 2001. Vitamin K-dependent Carboxylase. eLS. .

Author Information

  1. University of Wisconsin-Madison, Madison, Wisconsin, USA

Publication History

  1. Published Online: 25 APR 2001

Abstract

Proteins are posttranslationally modified by specific γ-glutamyl carboxylation. It is believed this reaction is the only known metabolic role of the vitamin K-dependent enzyme that carries out this carboxylation.

Keywords:

  • phylloquinone;
  • menaquinones;
  • vitamin K;
  • γ-carboxyglutamic acid;
  • warfarin