Standard Article

Regulatory Cascade

  1. Johan Van Lint1,
  2. Jackie R Vandenheede2

Published Online: 19 APR 2001

DOI: 10.1038/npg.els.0000867

eLS

eLS

How to Cite

Lint, J. V. and Vandenheede, J. R. 2001. Regulatory Cascade. eLS. .

Author Information

  1. 1

    Katholieke Universiteit Leuven, Leuven, Belgium

  2. 2

    Katholieke Universiteit Leuven, Leuven, Belgium

Publication History

  1. Published Online: 19 APR 2001

Abstract

An enzyme cascade is a regulatory system where one enzyme catalyses the covalent modification of another enzyme. Regulatory cascades are either unidirectional or cyclic; both types are important biological switches for the regulation of physiological processes.

Keywords:

  • cascades;
  • protein phosphorylation;
  • proteolysis;
  • glycogen metabolism;
  • blood clotting