Published Online: 19 APR 2001
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Gigant, B. and Knossow, M. 2001. Catalytic Antibodies. eLS. .
- Published Online: 19 APR 2001
It is possible to elicit antibodies that catalyse a target reaction by raising them against stable molecules mimicking intermediate species on the chemical pathway from substrate to product. These artificial biocatalysts are closer to enzymes than any other enzyme mimic. Recent progress and new strategies bode well for the practical use of catalytic antibodies.
- enzyme mimic;
- transition state analogue;