Standard Article

mRNA Splicing: Regulated and Differential

  1. Thomas A Cooper

Published Online: 22 MAR 2002

DOI: 10.1038/npg.els.0000897

eLS

eLS

How to Cite

Cooper, T. A. 2002. mRNA Splicing: Regulated and Differential. eLS. .

Author Information

  1. Baylor College of Medicine, Houston, Texas, USA

Publication History

  1. Published Online: 22 MAR 2002

Abstract

Alternative splicing is the process by which single genes express multiple messenger RNAs (mRNAs), and therefore multiple proteins, by differential processing of the primary transcript (pre-mRNA). The temporal and spatial regulation of protein expression by alternative splicing is determinative for such diverse biological processes as gender specification in Drosophila, commitment to apoptosis, and sound frequency recognition of individual hair cells in the avian cochlea.

Keywords:

  • alternative splicing;
  • pre-mRNA;
  • cell-specific regulation