Standard Article

T-cell Receptors

  1. Marc Bonneville,
  2. Xavier Saulquin

Published Online: 23 SEP 2005

DOI: 10.1038/npg.els.0000915



How to Cite

Bonneville, M. and Saulquin, X. 2005. T-cell Receptors. eLS. .

Author Information

  1. INSERM Unit 601, Nantes, France

Publication History

  1. Published Online: 23 SEP 2005

This is not the most recent version of the article. View current version (14 AUG 2015)


Antigen recognition by T lymphocytes is achieved via α/β or γ/δ T-cell receptors, which are both produced through somatic rearrangement of gene segments. Upon their engagement by antigens, T-cell receptors trigger a complex sequence of events that ultimately lead to T-cell activation.


  • T lymphocyte;
  • gene recombination;
  • antigen;
  • TCR α/β;
  • TCR γ/δ