Standard Article

Bacterial Replication Fork: Synthesis of Lagging Strand

  1. Hisao Masai

Published Online: 19 APR 2001

DOI: 10.1038/npg.els.0001049

eLS

eLS

How to Cite

Masai, H. 2001. Bacterial Replication Fork: Synthesis of Lagging Strand. eLS. .

Author Information

  1. Institute of Medical Science, University of Tokyo, Tokyo, Japan

Publication History

  1. Published Online: 19 APR 2001

This is not the most recent version of the article. View current version (19 APR 2010)

Abstract

How can an antiparallel DNA strand be duplicated by a DNA polymerase that synthesizes DNA in only one direction? What are the enzymatic limitations of DNA polymerases with respect to DNA duplex polarities?

Keywords:

  • DNA helicase;
  • okazaki fragment;
  • primosome;
  • discontinuous DNA synthesis;
  • DNA polymerase;
  • primer RNA