Published Online: 30 MAY 2001
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Segall, A. 2001. Site-specific Recombination. eLS. .
- Published Online: 30 MAY 2001
Site-specific recombination is defined as the rearrangement of two DNA partner molecules by specific enzymes performing recombination at their cognate pairs of sequences or target sites. Site-specific recombination, in contrast to homologous recombination, requires very little DNA homology between partner DNA molecules, is RecA-independent, and does not involve DNA replication at any stage.
- gene expression;
- chromosome segregation;
- gene targeting