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Histones: from Gene Organization to Biological Roles

  1. Detlef Doenecke

Published Online: 23 SEP 2005

DOI: 10.1038/npg.els.0001154

eLS

eLS

How to Cite

Doenecke, D. 2005. Histones: from Gene Organization to Biological Roles. eLS.

Author Information

  1. Georg-August-Universität Göttingen, Göttingen, Germany

Publication History

  1. Published Online: 23 SEP 2005

This is not the most recent version of the article. View current version (15 APR 2014)

Abstract

Histones are a group of highly conserved small basic proteins that form the major part of the protein moiety of eukaryotic chromosomes. Their function in structuring the nucleosomes as the basal chromosomal deoxynucleoprotein repeat units is modulated by several different types of posttranslational modifications and varied patterns of histone structure variants contributing to the nucleosome structure.

Keywords:

  • core histones;
  • linker histones;
  • posttranslational modification of histones;
  • acetylation of histones;
  • methylation of histones