Nucleosomes: Structure and Function
Published Online: 25 APR 2001
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Luger, K. 2001. Nucleosomes: Structure and Function. eLS.
- Published Online: 25 APR 2001
The structure of the nucleosome core particle, the basic repeating unit in eukaryotic chromatin, allows us to view the role of histones in regulating transcription, and in assembling specialized chromatin domains in a structural context. The organization of eukaryotic DNA into chromatin has fundamental implications for our understanding of all cellular processes that use DNA as a substrate.
- crystal structure;
- transcription regulation