Published Online: 22 MAR 2002
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Roosen, G., Velten, F. W. and Vos†, J.-M. H. 2002. Artificial Chromosomes. eLS. .
- Published Online: 22 MAR 2002
Artificial chromosomes are DNA molecules assembled in vitro from defined constituents, which guarantee stable maintenance of large DNA fragments with the properties of natural chromosomes. Artificial chromosomes are useful for genome sequencing programmes, for functional characterization of entire genomic regions and for the transduction of large DNA segments into human and nonhuman mammalian cells.
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