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Karyotype Analysis and Chromosome Banding

  1. Wendy A Bickmore

Published Online: 19 APR 2001

DOI: 10.1038/npg.els.0001160



How to Cite

Bickmore, W. A. 2001. Karyotype Analysis and Chromosome Banding. eLS. .

Author Information

  1. MRC Human Genetics Unit, Edinburgh, Scotland, UK

Publication History

  1. Published Online: 19 APR 2001


A series of reproducible bands across metaphase chromosomes can be revealed by some treatments. These chromosome bands not only allow the identification of normal and abnormal chromosomes but they also tell us about fundamental aspects of the chromatin structure and compartmentalization of the genome.


  • G/R bands;
  • heterochromatin;
  • replication;
  • gene distribution;
  • chromatin domains