Immunoglobulin Gene Construction: Human
Published Online: 28 MAY 2003
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Lucas, A. H. 2003. Immunoglobulin Gene Construction: Human. eLS. .
- Published Online: 28 MAY 2003
Human immunoglobulin genes exist as tandem arrays of gene segments that undergo somatic recombination and hypermutation during B-lymphocyte development. Together, these processes enable the generation of a vast repertoire of immunoglobulin molecules capable of recognizing and eliminating infectious agents.
- variable region;
- constant region;
- somatic recombination;