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Chromatin Diminution

  1. Heinz Tobler,
  2. Fritz Müller

Published Online: 19 APR 2001

DOI: 10.1038/npg.els.0001181



How to Cite

Tobler, H. and Müller, F. 2001. Chromatin Diminution. eLS. .

Author Information

  1. University of Fribourg, University of Fribourg, Fribourg, Switzerland

Publication History

  1. Published Online: 19 APR 2001


Chromatin diminution is defined as chromosomal fragmentation, followed by the elimination of part of the chromosome during mitosis. The process was first observed in early cleavage divisions of the Parascaris equorum embryo by Boveri in 1887, and later on was also found to occur in some other parasitic nematodes, copepods and ciliates.


  • chromatin diminution;
  • DNA elimination;
  • programmed genome rearrangement;
  • germline-soma differentiation;
  • nematode development