Mechanisms of X-inactivation
Published Online: 19 APR 2001
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Duthie, S. M. 2001. Mechanisms of X-inactivation. eLS. .
- Published Online: 19 APR 2001
X-inactivation involves the transcriptional silencing of one of the two X-chromosomes in the cells of female mammals. This process is controlled by elements present in the X-inactivation centre (Xic) which is required in cis for X-inactivation to occur.
- X chromosome inactivation;
- dosage compensation;
- X inactivation centre