DNA: Natural Single-stranded
Published Online: 19 APR 2001
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Ranu, R. S. 2001. DNA: Natural Single-stranded. eLS. .
- Published Online: 19 APR 2001
Single-stranded circular or linear viral genomes have been used as model systems to investigate the mechanisms of DNA replication and gene expression and for the development of highly versatile cloning vectors. Flexible single-stranded DNA can form hairpin/secondary structures by base pairing between regions of intramolecular sequence complementarity. Such structures are readily detected and appear to play important roles in virus-associated functions in vivo.
- single-stranded DNA;
- replicative form;
- secondary structure;
- overlapping genes