Published Online: 19 APR 2001
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Nigg, E. A. 2001. Mitosis. eLS. .
- Published Online: 19 APR 2001
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Mitosis is the creation of genetically identical cells from a single parental cell, involving the segregation of chromosomes to daughter cells, via a microtubule-based structure known as the mitotic spindle. Cells first undergo nuclear division, followed by cytoplasmic division (cytokinesis). Missing or extra chromosomes (aneuploidies) can cause miscarriages, birth defects and malignant tumours.
- chromosome segregation;
- microtubule-based spindle;
- cyclin-dependent kinase;