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Cholesterol, Steroid and Isoprenoid Biosynthesis

  1. Richard J Auchus1,
  2. Christopher M Adams2

Published Online: 23 SEP 2005

DOI: 10.1038/npg.els.0001393

eLS

eLS

How to Cite

Auchus, R. J. and Adams, C. M. 2005. Cholesterol, Steroid and Isoprenoid Biosynthesis. eLS. .

Author Information

  1. 1

    University of Texas, Southwestern Medical Center, Dallas, Texas, USA

  2. 2

    University of Texas, Southwestern Medical Center, Dallas, Texas, USA

Publication History

  1. Published Online: 23 SEP 2005

Abstract

Steroids, sterols, and many other natural products all derive from isoprenoid building blocks via two common biosynthetic pathways. The subsequent processing of the structural core yields specific products that possess diverse structures and biological activities.

Keywords:

  • sterols;
  • bile acids;
  • squalene;
  • mevalonate;
  • deoxyxylulose phosphate pathway;
  • steroidogenesis;
  • biosynthetic defects