Standard Article

Lipases: Digestion of Neutral Lipids; Physiological and Pathological Implications

  1. Margit Hamosh

Published Online: 23 SEP 2005

DOI: 10.1038/npg.els.0001395

eLS

eLS

How to Cite

Hamosh, M. 2005. Lipases: Digestion of Neutral Lipids; Physiological and Pathological Implications. eLS. .

Author Information

  1. Georgetown University Medical Center, Washington, District of Columbia, USA

Publication History

  1. Published Online: 23 SEP 2005

Abstract

Fat digestion is a complex process that starts in the stomach through the action of gastric lipase and continues in the intestine, where colipase-dependent pancreatic lipase and cholesterol ester lipase complete the process of triglyceride and cholesteryl ester hydrolysis, respectively. Bile salts and partial products of triglyceride hydrolysis are essential for the emulsification of these nonpolar lipids in the aqueous milieu of the intestinal lumen.

Keywords:

  • gastric lipase;
  • pancreatic lipases;
  • colipase;
  • milk lipase;
  • newborns