Site-specific Recombination in Chromosome Function
Published Online: 25 APR 2001
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Sherratt, D. J. 2001. Site-specific Recombination in Chromosome Function. eLS. .
- Published Online: 25 APR 2001
Site-specific recombination leads to the integration, deletion or inversion of defined DNA segments by conservative breakage–rejoining reactions at defined recombination sites. It functions to integrate and excise extrachromosomal elements into and out of genomes, to maintain circular replicons at the correct copy number in a monomeric state, and to mediate inversion gene switches.
- site-specific recombination;