Published Online: 19 APR 2001
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Walter, J. and High, K. 2001. Haemophilias. eLS. .
- Published Online: 19 APR 2001
Haemophilia is a hereditary bleeding disorder caused by a deficiency of one of two plasma clotting factors, factor VIII or factor IX. The clinical symptoms of this X-linked recessive disease vary depending on the level of activity of the affected factor. Patients may be asymptomatic, except in the face of trauma or surgery, or suffer from mild to severe, often spontaneous, haemorrhage.
- bleeding disorder;
- clotting factor;
- gene therapy