Published Online: 11 MAR 2004
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Devoret, R. 2004. Mutation. eLS. .
- Published Online: 11 MAR 2004
A mutation is a DNA change that is recorded durably and passed on to the offspring. A number of mutations in germ cells have detrimental effects for they often cause hereditary diseases. Likewise, mutations that accumulate in body cells can generate cancers. Nevertheless, a large number of mutations are neutral in their normal environment. The few advantageous mutations that occur are generally maintained. Mutations that arise at random are constantly sifted through by a selective environment. This dual process works as the driving force of evolution.
- ames test;
- DNA damage;
- DNA replication error