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Acute Lymphoblastic Leukaemia

  1. Judith M Chessells

Published Online: 19 APR 2001

DOI: 10.1038/npg.els.0002172



How to Cite

Chessells, J. M. 2001. Acute Lymphoblastic Leukaemia. eLS. .

Author Information

  1. Institute of Child Health, University College, London, UK

Publication History

  1. Published Online: 19 APR 2001

This is not the most recent version of the article. View current version (5 MAY 2014)


Lymphoblastic leukaemia is a heterogeneous disease of children and adults resulting from clonal expansion of progenitor cells. Treatment with intensive cytotoxic therapy is effective in the majority of children, but treatments for adults are less effective, probably because the disease originates from relatively drug-resistant stem cells.


  • leukaemia;
  • clinical trials;
  • bone marrow transplantation;
  • molecular genetics