Standard Article

Polyketides

  1. Ronald Bentley

Published Online: 25 APR 2001

DOI: 10.1038/npg.els.0002343

eLS

eLS

How to Cite

Bentley, R. 2001. Polyketides. eLS. .

Author Information

  1. University of Pittsburgh, Pennsylvania, USA

Publication History

  1. Published Online: 25 APR 2001

Abstract

Polyketides are a large group of secondary metabolites of varied structure with carbon chains formed by decarboxylative addition of malonyl thioesters to a starter unit. Some are useful drugs, others are toxic or carcinogenic; genetic engineering may lead to new polyketide drugs.

Keywords:

  • combinatorial biosynthesis;
  • genetic engineering;
  • polyacetates;
  • polyketides;
  • secondary metabolites