hnRNP: Methods for Preparation
Published Online: 19 APR 2001
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Tan, J.-h. and LeStourgeon, W. M. 2001. hnRNP: Methods for Preparation. eLS. .
- Published Online: 19 APR 2001
During transcription in higher eukaryotes, the elongating pre-messenger RNA is bound by a unique set of abundant nuclear proteins to form a repeating array of 20–22-nm particles termed 30–40S heterogeneous nuclear ribonucleoprotein (hnRNP) particles. A variety of methods exist for the isolation and purification of hnRNP complexes and for the in vitro assembly of hnRNP assembly intermediates.
- RNA-binding protein