snRNPs: Methods for Purification
Published Online: 19 APR 2001
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Kastner, B. 2001. snRNPs: Methods for Purification. eLS. .
- Published Online: 19 APR 2001
Small nuclear ribonucleoprotein particles (snRNPs) are essential cofactors for the nuclear splicing of pre-mRNA introns. The method best suited to the purification of snRNPs is affinity chromatography combined with competitive elution.
- pre-mRNA splicing;
- RNA–protein interaction