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Solid-phase Peptide Synthesis: Fmoc

  1. Chi C Yang

Published Online: 3 MAY 2005

DOI: 10.1038/npg.els.0002693

eLS

eLS

How to Cite

Yang, C. C. 2005. Solid-phase Peptide Synthesis: Fmoc. eLS. .

Author Information

  1. SynPep Corporation, California, USA

Publication History

  1. Published Online: 3 MAY 2005

Abstract

Synthetic peptides are increasingly important in biochemical, pharmacological, neurobiological, enzymological and molecular biological research. Use of Fmoc as temporary amino-protecting group allows solid-phase peptide synthesis with a milder acid cleavage process. Other advances in the ligation approach provide further potential for peptide synthesis.

Keywords:

  • resin;
  • loading;
  • protecting group;
  • cleavage;
  • ligation;
  • SPPS