Standard Article

Crystallization of Proteins and Protein–Ligand Complexes

  1. Alexander McPherson

Published Online: 25 APR 2001

DOI: 10.1038/npg.els.0002718

eLS

eLS

How to Cite

McPherson, A. 2001. Crystallization of Proteins and Protein–Ligand Complexes. eLS. .

Author Information

  1. University of California, Irvine, California, USA

Publication History

  1. Published Online: 25 APR 2001

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Abstract

Many factors affect the crystallization of macromolecules such as proteins; whether it occurs at all, the rate of crystallization, and the quality of the product. Crystallization conditions are optimized by various techniques that allow one to screen as many combinations of parameters as possible, based on previous experience wherever possible.

Keywords:

  • X-ray diffraction;
  • structural biology;
  • viruses;
  • protein structure;
  • crystallography