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Immuno-electron Microscopy

  1. Heinz Schwarz1,
  2. Heinz Hohenberg2

Published Online: 25 APR 2001

DOI: 10.1038/npg.els.0003000

eLS

eLS

How to Cite

Schwarz, H. and Hohenberg, H. 2001. Immuno-electron Microscopy. eLS. .

Author Information

  1. 1

    Max Planck Institute for Developmental Biology, Tübingen, Germany

  2. 2

    Heinrich Pette Institute for Experimental Virology and Immunology, Hamburg, Germany

Publication History

  1. Published Online: 25 APR 2001

Abstract

Immuno-electron microscopy combines the specificity and sensitivity of immunological methods with the high structural resolution of electron microscopy, providing an in situ correlation and visualization of antigen-binding sites and ultrastructure.

Keywords:

  • particulate markers;
  • colloidal gold;
  • chemical fixation;
  • cryofixation;
  • on-section labelling