Protein Folding: Overview of Pathways
Published Online: 25 APR 2001
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Wedemeyer, W. J. and Scheraga, H. A. 2001. Protein Folding: Overview of Pathways. eLS.
- Published Online: 25 APR 2001
Most proteins can function only if they are folded – i.e. if they have adopted a specific, stable tertiary structure. The ‘protein folding problem’ is to determine how and why the initially unstructured protein converges to this native structure. A typical sequence of structural changes during the folding of a protein molecule is referred to as a folding pathway.
- protein folding;
- folding pathways;
- hydrophobic collapse;
- kinetic models