Standard Article

Peptidylproline cistrans-Isomerases

  1. Gunter Fischer1,
  2. Franz-Xaver Schmid2

Published Online: 19 APR 2001

DOI: 10.1038/npg.els.0003020



How to Cite

Fischer, G. and Schmid, F.-X. 2001. Peptidylproline cistrans-Isomerases. eLS. .

Author Information

  1. 1

    Martin Luther University Halle-Wittenberg, Halle/Saale, Germany

  2. 2

    University of Bayreuth, Bayreuth, Germany

Publication History

  1. Published Online: 19 APR 2001

This is not the most recent version of the article. View current version (14 MAY 2015)


Peptidylproline cistrans-isomerases are ubiquitous enzymes that bind to Xaa-Pro peptide bonds in proteins and catalyse their isomerization. In addition to their role as folding helpers they are involved in multiple functions including cellular regulation.


  • cyclophilin;
  • FKBP;
  • parvulin;
  • protein folding