Standard Article

Genome, Proteome, and the Quest for a Full Structure–Function Description of an Organism

  1. Li-Wei Hung,
  2. Sung-Hou Kim

Published Online: 19 APR 2001

DOI: 10.1038/npg.els.0003024

eLS

eLS

How to Cite

Hung, L.-W. and Kim, S.-H. 2001. Genome, Proteome, and the Quest for a Full Structure–Function Description of an Organism. eLS. .

Author Information

  1. Lawrence Berkeley National Laboratory and University of California, Berkeley, Berkeley, USA

Publication History

  1. Published Online: 19 APR 2001

This is not the most recent version of the article. View current version (15 MAR 2013)

Abstract

Using sequencing techniques developed in the 1990s, the genome projects have now successfully identified all the genes in several organisms encrypted in a four-letter alphabet. The gene products – proteins and RNAs coded by the genes – are the actual nuts and bolts of a living organism and the elucidation of their function and how they interact to sustain life remains one of the biggest challenges of the twenty-first century.

Keywords:

  • genome;
  • proteome;
  • DNA;
  • RNA;
  • protein;
  • ORF;
  • pathway;
  • proteomics