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Immunoglobulin Fold: Structures of Proteins in the Immunoglobulin Superfamily

  1. Israel M Gelfand1,
  2. Cyrus Chothia2,
  3. Alexander E Kister1

Published Online: 19 APR 2001

DOI: 10.1038/npg.els.0003051

eLS

eLS

How to Cite

Gelfand, I. M., Chothia, C. and Kister, A. E. 2001. Immunoglobulin Fold: Structures of Proteins in the Immunoglobulin Superfamily. eLS. .

Author Information

  1. 1

    Rutgers University, Piscataway, New Jersey, USA

  2. 2

    MRC Laboratory of Molecular Biology, Cambridge, UK

Publication History

  1. Published Online: 19 APR 2001

Abstract

Proteins of the immunoglobulin fold are built of homologous domains of approximately 100 residues and with a structure formed by two β sheets packed face to face. Functions of the proteins are mainly in the immune system, cell–cell recognition or in the structural organization and regulation of muscle.

Keywords:

  • immunoglobulin structures;
  • gene structures;
  • structural determinants;
  • binding sites