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GTP-binding Loop

  1. Guangpu Li

Published Online: 26 MAR 2003

DOI: 10.1038/npg.els.0003052



How to Cite

Li, G. 2003. GTP-binding Loop. eLS. .

Author Information

  1. University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA

Publication History

  1. Published Online: 26 MAR 2003


The GTP-binding loop is an evolutionarily conserved structure found in the GTPase superfamily of proteins. The GTP-binding loop enables GTPases to bind and hydrolyse GTP molecules and makes them excellent regulators of cellular processes.


  • GTPase;
  • GTP hydrolysis;
  • guanine nucleotide;
  • molecular switch;
  • Ras