Mass Spectrometry: Analysis of Two-dimensional Protein Gels
Published Online: 24 OCT 2002
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Lim, H. and Yates, J. R. 2002. Mass Spectrometry: Analysis of Two-dimensional Protein Gels. eLS.
- Published Online: 24 OCT 2002
Matrix-assisted laser desorption/ionization mass spectrometry and electrospray tandem mass spectrometry, coupled with liquid chromatography, enable high-throughput protein identification and further characterization, such as post-translational modification, of proteins, after initial separation by two-dimensional gel electrophoresis.
- two-dimensional gel electrophoresis;
- mass spectrometry;
- posttranslational modification