Mass Spectrometry: Peptide Sequencing
Published Online: 25 APR 2001
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Watson, J. T. 2001. Mass Spectrometry: Peptide Sequencing. eLS. .
- Published Online: 25 APR 2001
Electrospray and MALDI (matrix-assisted laser desorption ionization) are two versions of desorption/ionization that allow modern mass spectrometry to be applied to the analysis of peptides and proteins. In addition to a direct indication of the molecular weight, the sequence of amino acids in a peptide can be deduced from the fragmentation pattern (the mass spectrum itself).
- signal suppression;
- mass spectrum;
- matrix-assisted laser desorption ionization