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Nucleic Acids: Thermal Stability and Denaturation

  1. Mitchel J Doktycz

Published Online: 24 OCT 2002

DOI: 10.1038/npg.els.0003123

eLS

eLS

How to Cite

Doktycz, M. J. 2002. Nucleic Acids: Thermal Stability and Denaturation. eLS. .

Author Information

  1. Oak Ridge National Laboratory, Oak Ridge, Tennessee, USA

Publication History

  1. Published Online: 24 OCT 2002

Abstract

Nucleic acid structures can have different stabilities that depend on a variety of factors that include the nucleic acid sequence, the structure adopted, and the solution environment. Together, these factors influence the thermal stability of the complex.

Keywords:

  • DNA melting;
  • RNA melting;
  • duplex stability;
  • base pairing