Standard Article

Protein–DNA Interactions: Techniques Used

  1. Mark A Strauch

Published Online: 19 APR 2001

DOI: 10.1038/npg.els.0003128

eLS

eLS

How to Cite

Strauch, M. A. 2001. Protein–DNA Interactions: Techniques Used. eLS. .

Author Information

  1. University of Maryland, Baltimore, Maryland, USA

Publication History

  1. Published Online: 19 APR 2001

Abstract

A plethora of biochemical and biophysical techniques are used to investigate various aspects of protein–DNA interactions. Some of the more common and useful of these are filter binding, the gel mobility shift assay, a large group of related techniques broadly categorized as footprinting, high-resolution microscopy and spectroscopy.

Keywords:

  • protein–DNA complexes;
  • techniques;
  • DNA-binding proteins