Protein–Nucleic Acid Interaction: Major Groove Recognition Determinants
Published Online: 25 APR 2001
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Xiong, Y. and Sundaralingam, M. 2001. Protein–Nucleic Acid Interaction: Major Groove Recognition Determinants. eLS. .
- Published Online: 25 APR 2001
Protein–nucleic acid interactions play a crucial role in central biological processes. It is known that the most common binding element of proteins is an α helix and the primary binding site on DNA is in the major groove. Some general rules of the α helix binding to the DNA major groove have been derived, but there is no general code (one-to-one correspondence) for recognition.
- protein–nucleic acid complexes;
- zinc finger;
- α helix binding;
- major groove interactions