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Transcription Activation in Eukaryotic Cells

  1. Alcide Barberis,
  2. Michael Petrascheck

Published Online: 28 MAY 2003

DOI: 10.1038/npg.els.0003303



How to Cite

Barberis, A. and Petrascheck, M. 2003. Transcription Activation in Eukaryotic Cells. eLS. .

Author Information

  1. ESBATech AG, Zürich-Schlieren, Switzerland

Publication History

  1. Published Online: 28 MAY 2003


Transcription activation is the first step in eukaryotic gene expression. Gene regulation, which is about turning on and off expression of specific protein-coding genes in response to environmental changes, during development and in differentiated cells, widely occurs at the level of transcription activation. This is mostly achieved by DNA-binding proteins that can control the specificity of the RNA polymerase II enzyme.


  • promoters;
  • enhancers;
  • transcription;
  • activators;
  • recruitment