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DNA Replication: Prokaryotes and Yeast

  1. Derek J Hoelz,
  2. Robert J Hickey,
  3. Linda H Malkas

Published Online: 11 MAR 2004

DOI: 10.1038/npg.els.0003744



How to Cite

Hoelz, D. J., Hickey, R. J. and Malkas, L. H. 2004. DNA Replication: Prokaryotes and Yeast. eLS. .

Author Information

  1. Indiana University School of Medicine, Indianapolis, IN, USA

Publication History

  1. Published Online: 11 MAR 2004


An organism's ability to pass on genetic information to further generations requires the accurate reproduction of its genomic DNA, a process termed DNA replication. Examination of the events that take place during DNA replication has revealed numerous well-orchestrated protein–protein interactions and enzymatic reactions, which ultimately leads to synthesis of an essentially identical replica of the cell's complete genome.


  • bacteria;
  • bacteriophages;
  • initiation;
  • elongation