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Semliki Forest Virus Expression System

  1. Mathilda Sjöberg,
  2. Maria Ekström

Published Online: 23 SEP 2005

DOI: 10.1038/npg.els.0003860



How to Cite

Sjöberg, M. and Ekström, M. 2005. Semliki Forest Virus Expression System. eLS. .

Author Information

  1. Karolinska Institute, Huddinge, Sweden

Publication History

  1. Published Online: 23 SEP 2005

This is not the most recent version of the article. View current version (15 JUL 2014)


Eukaryotic cells can be programmed to synthesize foreign proteins by infection with recombinant Semliki Forest virus. The foreign protein is produced at a high level from about 4 h after infection, whereas cell-derived protein synthesis is shut down.


  • mammalian protein expression;
  • biotechnology