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Protein–DNA Interactions

  1. Marianne Rooman,
  2. René Wintjens

Published Online: 3 MAY 2005

DOI: 10.1038/npg.els.0003906



How to Cite

Rooman, M. and Wintjens, R. 2005. Protein–DNA Interactions. eLS. .

Author Information

  1. Free University of Brussels, Brussels, Belgium

Publication History

  1. Published Online: 3 MAY 2005

This is not the most recent version of the article. View current version (16 MAR 2015)


The control of the information stored in the genome is managed by DNA-binding proteins, which are therefore of fundamental importance to cellular life. A wide diversity of such proteins, exhibiting various DNA-binding modes, specificities and functions, is observed in all living organisms.


  • DNA-binding enzymes;
  • transcription regulation;
  • structure motifs;
  • proteins–DNA affinity;
  • binding specificity