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Protein–DNA Interactions

  1. Marianne Rooman,
  2. René Wintjens

Published Online: 3 MAY 2005

DOI: 10.1038/npg.els.0003906



How to Cite

Rooman, M. and Wintjens, R. 2005. Protein–DNA Interactions. eLS. .

Author Information

  1. Free University of Brussels, Brussels, Belgium

Publication History

  1. Published Online: 3 MAY 2005


The control of the information stored in the genome is managed by DNA-binding proteins, which are therefore of fundamental importance to cellular life. A wide diversity of such proteins, exhibiting various DNA-binding modes, specificities and functions, is observed in all living organisms.


  • DNA-binding enzymes;
  • transcription regulation;
  • structure motifs;
  • proteins–DNA affinity;
  • binding specificity