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Free Radicals and Other Reactive Species in Disease

  1. Barry Halliwell

Published Online: 3 MAY 2005

DOI: 10.1038/npg.els.0003913

eLS

eLS

How to Cite

Halliwell, B. 2005. Free Radicals and Other Reactive Species in Disease. eLS. .

Author Information

  1. National University of Singapore, Singapore

Publication History

  1. Published Online: 3 MAY 2005

This is not the most recent version of the article. View current version (16 MAR 2015)

Abstract

Free radicals can be generated in a wide variety of chemical and biological systems, including the formation of plastics, the ageing of paints, the combustion of fuels and in the human body. In living organisms, the levels of free radicals and other ‘reactive species’ are controlled by a complex web of antioxidant defences, which minimize (but do not completely prevent) oxidative damage to biomolecules.

Keywords:

  • free radical;
  • antioxidant;
  • superoxide;
  • lipid peroxidation;
  • oxidative stress;
  • mutation