Published Online: 23 SEP 2005
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Bianco, P. R. and Kowalczykowski, S. C. 2005. RecA Protein. eLS. .
- Published Online: 23 SEP 2005
The RecA protein of Escherichia coli is the prototypic deoxyribonucleic acid (DNA) strand exchange protein. It assembles on single-stranded DNA to form a helical nucleoprotein filament that is the active species for all RecA protein-dependent functions. This protein–DNA complex is responsible for three mutually exclusive functions: DNA recombination, induction of the DNA-damage SOS response and SOS-induced mutagenesis.
- DNA strand exchange;
- genetic recombination;
- SOS response;
- SOS mutagenesis;
- nucleoprotein filament;
- LexA repressor