Standard Article


  1. John C Wallace1,
  2. Greg J Barritt2

Published Online: 23 SEP 2005

DOI: 10.1038/npg.els.0003930



How to Cite

Wallace, J. C. and Barritt, G. J. 2005. Gluconeogenesis. eLS. .

Author Information

  1. 1

    University of Adelaide, Adelaide, South Australia, Australia

  2. 2

    Flinders University School of Medicine, Adelaide, South Australia, Australia

Publication History

  1. Published Online: 23 SEP 2005

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The gluconeogenic pathway, which is found in the liver and kidney, involves the synthesis of glucose from three-carbon precursors such as lactate, alanine and glycerol. The main function of gluconeogenesis is to supply glucose to tissues, such as the brain and red blood cells, that depend on glucose as their main or sole energy source.


  • glucose homeostasis;
  • pyruvate;
  • lactate;
  • liver;
  • fatty acids