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Chromosome Function: Sex Differences

  1. Jacob L Mueller,
  2. Mariana F Wolfner

Published Online: 23 SEP 2005

DOI: 10.1038/npg.els.0003939



How to Cite

Mueller, J. L. and Wolfner, M. F. 2005. Chromosome Function: Sex Differences. eLS. .

Author Information

  1. Cornell University, Ithaca, New York, USA

Publication History

  1. Published Online: 23 SEP 2005


The distinct development of females and males is usually the consequence of differences in their sex chromosome constitution. To compensate for these differences, the sexes adjust the expression of sex-linked genes. Some inheritance patterns depend on the sex or sex chromosome make-up of a parent.


  • sex chromosomes (X, Y, Z, W);
  • sex determination;
  • dosage compensation;
  • female/male;
  • sex-based inheritance patterns